UCLA & Cedars-Sinai study re: leukemia.
This is an abstract from a very important study regarding the effects of ganoderma regarding leukemia. I don’t have the entire study, though those who have a high interest can obtain it. Follow the Elsevier pubs link. It costs $31.50 (US).
Below is the abstract from the study. Note the use of the term “profound”. These are medical research professionals. They don’t use the term “profound” lightly. If it was slight they would have said “slight”, likewise for “significant”, but they said “profound“. I can’t emphasize this enough. Note the word “apoptosis”, which means death. In this use, it means the death of the cells of leukemia.
If you, or a loved one are suffering from leukemia, I would recommend you refer your medical professionals to this study.
Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States. MullerCI@cshs.org
Ganoderma lucidum causes apoptosis in leukemia, lymphoma and multiple myeloma cells.
Müller CI, Kumagai T, O’Kelly J, Seeram NP, Heber D, Koeffler HP.
Over many centuries, herbal remedies have treated a variety of ailments. This empiric observational approach has produced a number of leads for formulated medicines. Ganoderma lucidum extract was screened for its anti-proliferative activity using a panel of 26 human cancer cell lines. The six most sensitive hematologic cell lines were: HL-60 (ED50 26 microg/ml), U937 (63 microg/ml), K562 (50 microg/ml), Blin-1 (38 microg/ml), Nalm-6 (30 microg/ml) and RPMI8226 (40 microg/ml). Cell cycle analyses revealed a G2/M arrest, most prominently in HL-60 cells. Four hematopoietic cell lines (HL-60, Blin-1, U937, RPMI8226) were examined for apoptosis, which ranged between 21 and 92%. After exposure to G. lucidum extract, HL-60 cells became multinucleated with an increased DNA content. These results indicate that G. lucidum extract has a profound activity against leukemia, lymphoma and multiple myeloma cells and may be a novel adjunctive therapy for the treatment of hematologic malignancies.
PMID: 16423392 [PubMed - indexed for MEDLINE]
on August 6, 2009 at 2:59 pm
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